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Dr. Allen Frances: January 2011 Archives

January 2011 Archives

An Independent View of DSM-5

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Gary Greenberg, Ph.D., is a psychotherapist, author, teacher and historian of psychiatric diagnosis. His writings are characterized by penetrating insight, elegant wordsmithing, entertaining storytelling, and a dig-deep, no-holds-barred search for underlying meaning. I rate his recently published "Manufacturing Depression" as one of the best books ever written on any psychiatric diagnosis.

I met Dr. Greenberg about three months ago when he interviewed me as part of his intensive research for an article on DSM-5. It has just appeared in the January edition of Wired.

The article illustrates the numerous deficiencies Dr. Greenberg has uncovered in the DSM-5 process -- its secrecy, defensiveness, excessive ambition and disorganized execution. He shows how these have resulted in strange DSM-5 products -- particularly the proposals for a psychosis risk syndrome and complex dimensional measures. Anyone at all interested in DSM-5 and its impact on patients and society should definitely read Greenberg's piece (and weep).

I have been attempting to highlight these same themes, but Dr. Greenberg does it more elegantly and comprehensively than I possibly could -- both because he is a much better writer and because he has interviewed and can assess all the major players on both sides of the debate. He combines the sensibilities of a diagnostic theorist with the skills of an investigative journalist. 

Not all of his findings could be included in the Wired piece. Additional fascinating details about the APA handling of DSM-5 can be found on Dr. Greenberg's blog.

 A large new study from Australia found that DSM-5 would cause a skyrocketing 60-percent increase in the rate of alcohol-use disorders. The authors are neutral on whether the consequences of this huge jump would be positive or negative. Their study was not designed to determine whether the new "problem drinkers" caught in the wide net cast by DSM-5 would benefit -- or whether they lack clinically significant impairment and might be harmed by misidentification and unnecessary stigma.

Some thoughts:

1) This kind of comparison between rates of diagnosis using DSM-5 versus DSM IV urgently needs to be done for every change suggested in DSM-5. Otherwise, its makers will have no way of judging the possibly enormous impact of DSM-5 in pushing the boundary of mental disorder deep into what has heretofore been considered normality. Note that this study on rates of alcohol disorder was performed independent of the work on DSM-5. Unaccountably (and irresponsibly), the DSM-5 field trials have altogether avoided studying impact on rates and will therefore not have this necessary information for any of its changes in other diagnoses.

DSM-5 will be flying blind to its impact.

2) If, as seems probable, the new DSM-5 proposals for other diagnoses encourage similar large jumps in diagnostic rates, the concept of psychiatric disorder will be trivialized beyond recognition. We already have a diagnostic system whose low thresholds pin a diagnostic label on 45 million Americans every year. The further watering down of definitional standards will make psychiatric diagnosis so ubiquitous as to be almost meaningless -- and divert scarce resources away from the patients with severe psychiatric disorders who really need them.

3) The obvious next step is to determine more about the risks and benefits of such a huge swing in diagnostic practice -- both to the individuals newly labeled as mentally disordered by DSM-5 and to the nation's health-care policy.

4) Decisions of such huge import to people and policy should not be left to a small group of narrowly focused experts. Experts are always biased to prefer lower thresholds so as to avoid missed diagnoses. They are consistently insensitive to the risks of overdiagnosis. I discussed this in more detail in a recent blog

5) DSM-5 changes should not be made in a fast-draw, shoot-from-the-hip manner, without any study of their effect on rates and possibly profound negative consequences. The design of the DSM-5 field trials should be revised now, before it is too late, to determine how each proposed change will influence rates of disorder and to assess the risks of overdiagnosis. 

DSM-5: Dissent From Within

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Many people associated with DSM-5 have privately expressed their serious doubts to me, but felt muzzled into public silence by constraining confidentiality agreements and loyalty to the process. Gary Greenberg's recent DSM-5 piece in Wired offers a set of dispirited quotes from discouraged work group members-but again he elicited them only under the promise of strict anonymity. Until now, the only people connected to DSM-5 to express public displeasure were the two who have resigned from it.

John Livesley, a highly respected member of the Personality Disorders (PD) Work Group, has now broken this fortress defensiveness and enforced wall of silence. He has published a brilliantly reasoned critique titled "Confusion and Incoherence in the Classification of Personality Disorder: Commentary on the Preliminary Proposals for DSM-5."

The title says it all -- the PD proposal is a pretentious emperor without any clothes. Dr. Livesley systematically catalogs all its many defects: breathtakingly radical change based on questionable empirical support, lack of reasonable rationale, mind-boggling and incoherent complexity, poor taxonomic methods and inconsistency among components. This is a proposal that will never be used by clinicians, will greatly hamper personality disorder research, and will blacken the reputation of dimensional diagnosis. It will reduce the credibility of personality disorder as an important clinical issue, leading patients with severe personality problems to be misdiagnosed and hence mistreated or not treated at all.

Opposition to the proposal is virtually unanimous among personality disorder experts. Strong critiques have been, or soon will be, published in the American Journal of Psychiatry; the Journal of Abnormal Psychology; the Journal of Personality Disorders; and Personality Disorders: Theory, Research, and Treatment. Only a very flawed and unnecessarily closed DSM 5 process could have allowed the survival to this late stage of such bizarrely misguided and idiosyncratic suggestions.

Clearly, breaking with his colleagues was not an easy step for Dr. Livesley, or one he took lightly. The confidentiality restrictions turned out not to be a problem -- he bypassed them simply by using only information that is already available in the public domain. His more difficult choice was whether to expose the follies of the PD work group -- given his understandable bond of loyalty to colleagues on the committee. Fortunately, this was trumped by four much stronger and even more admirable loyalties -- "to intellectual honesty, respect for empirical findings, and concern for the future of the field and patient care."

I know that many other DSM-5 workers are similarly disturbed by the lack of organization in the DSM-5 process and the wayward nature of many of its proposals. They have heretofore been frozen into immobile public silence by some combination of team spirit, passivity, the confidentiality agreements, distaste for controversy and fear of retaliation. Dr Livesley's well-reasoned dissenting opinion provides DSM-5 participants with a model of responsible behavior under difficult circumstances. Principled and open dissent is a time-honored way reconciling the conflicting pressures they must feel. If this is a good enough approach for the Supreme Court, why not have it inform a DSM-5 process that has become the supreme court of diagnostic judgment?

Everyone involved with DSM-5 should follow Dr. Livesley's example and at last feel encouraged to speak openly. They needn't worry about confidentiality agreements if comments focus on information that is posted and public. Intellectual honesty and concern for patient welfare trump narrow loyalties to colleagues or guild interest.

It is not too late to save DSM-5 from itself -- if only those working on it will finally break free of groupspeak and share their thoughts with the field -- as they should have been encouraged to do from the very outset. The current sad state of DSM-5 has been caused by secrecy and defensiveness. The only salvation is completely frank and open discussion. Great thanks are owed to Dr. Livesley for having demonstrated the wisdom, responsibility, and courage to light this path for his colleagues.

Dr. Livesley's article can be found online in the current issue of the journal Psychological Injury and the Law. I recommend it highly to anyone interested in the conceptual issues that underlie personality disorder diagnosis and, more broadly, to those concerned with the problems that have bedeviled the development of DSM-5. He will be publishing additional thoughts in a spring issue of the Journal of Personality Disorders devoted to the DSM-5 suggestions.

DSM-5 Year-End Summary

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There have been three positive developments:

1) The appointment of a work group reporting to the APA Board of Trustees (BOT) charged with independently reviewing the scientific evidence supporting DSM-5 proposals. Too bad it is not really independent and that the report will be confidential.

2) The increasing activity of the Assembly provides a sorely needed governance check to fill the void created by an almost total absence of BOT leadership. 

3) The example set by John Livesley of the Personality Disorders work group in courageously publishing a dissent that details the foolishness of its proposals. Perhaps others working on DSM-5 will follow his lead and open a much-needed public discussion of other potentially harmful DSM proposals. 

 The rest of the DSM 5 news continues to be extremely worrisome. 

1) Aside from being off point, the DSM-5 field trials have fallen far behind schedule. Originally meant to start in July 2009, then rescheduled to begin in July of 2010, the project is still not fully off the ground. An impossibly complicated design guarantees further inevitable delays. Poor planning and disorganized execution will inevitably lead to rushed attempts to cut corners in order to meet the irrevocable May 2013 publication deadline. The field trials will almost surely turn out to have been a colossal waste of time, money, and effort. 

2) The BOT remains passive and spends almost no time or thought on DSM-5, somehow not understanding how crucial it is for the APA and for our patients. 

3) For mysterious reasons, the posting of all the latest DSM 5 criteria sets has been delayed. 

4) The reconciliation of DSM-5 codes with the ICD-10-CM codes has been left to the last minute and is being done carelessly. 

5) The leadership did finally appoint a group charged with writing the DSM-5 text. But the effort is off to a very late start and has a decentralized structure unlikely to produce a consistent and well-organized document. In the preparation of DSM-IV, I found text writing by far the most time consuming, demanding, and onerous task. I fear that DSM-5 may not have the time and expertise to write a readable manual. 

All in all, another year that has largely been wasted. Time is running out. 

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